We woke up today to some some bad news in our mailbox. While we were sleeping, the Senate and House voted in new legislation which bans the possession and sale of 26 “new” synthetic drugs. Unfortunately, these are drugs that have not been studied in any sorts of clinical settings, and have definite possibilities for clinical use. These substances have now been given the death branding of Schedule I. Without having been studied, they have been judged to have “a high potential for abuse” and “no currently accepted medical use”.
I received this email this morning from the DEA:
The substances added to Schedule I of the Controlled Substances Act also include 9 different 2C chemicals, and 15 different synthetic cannabanoids…
…In addition to explicitly naming 26 substances, the legislation creates a new definition for “cannabamimetic agents,” creating criteria by which similar chemical compounds are controlled.
The legislation in question is S. 3187, the Food and Drug Administration Safety and Innovation Act. The amendment in question I believe is amendment 2146 , which was sponsored by Senator Rob Portman of Ohio. The specific list of controlled substances is available here. (EDIT: Library of Congress isn’t letting me link specifically to it, so I am posting it below this article). It is important for all of us to promote safe and responsible drug use, and to help people who have issues with drug abuse seek help. ProjectKnow.com is a good resource if you or someone you know is struggling with drug addiction. With SmarterNootropics, our mission is to promote safe responsible usage of Nootropics for the positive benefit of all.
With all these new legislations, we at smarternootropics thought it prudent to inform all our fellow nootropic enthusiasts. Specifically, one of the chemicals affected, 2C-D, is one which has been considered by many in the nootropic field to be a prime candidate for cognitive enhancement in low dosages. We are quite saddened to learn about this today, as action such as this limits one’s ability to harness the power of these substances for self betterment. With that said, we look onward with hopes of one day bringing you all a news report about drug laws based in research and facts, and better, more powerful nootropics.
LIST OF CONTROLLED SUBSTANCES
SEC. 1142. ADDITION OF SYNTHETIC DRUGS TO SCHEDULE I OF THE CONTROLLED SUBSTANCES ACT.
(a) Cannabimimetic Agents.–Schedule I, as set forth in section 202(c) of the Controlled Substances Act (21 U.S.C. 812(c)) is amended by adding at the end the following:
“(d)(1) Unless specifically exempted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of cannabimimetic agents, or which contains their salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation.
“(2) In paragraph (1):
“(A) The term `cannabimimetic agents’ means any substance that is a cannabinoid receptor type 1 (CB1 receptor) agonist as demonstrated by binding studies and functional assays within any of the following structural classes:
“(i) 2-(3-hydroxycyclohexyl)phenol with substitution at the 5-position of the phenolic ring by alkyl or alkenyl, whether or not substituted on the cyclohexyl ring to any extent.
“(ii) 3-(1-naphthoyl)indole or 3-(1-naphthylmethane)indole by substitution at the nitrogen atom of the indole ring, whether or not further substituted on the indole ring to any extent, whether or not substituted on the naphthoyl or naphthyl ring to any extent.
“(iii) 3-(1-naphthoyl)pyrrole by substitution at the nitrogen atom of the pyrrole ring, whether or not further substituted in the pyrrole ring to any extent, whether or not substituted on the naphthoyl ring to any extent.
“(iv) 1-(1-naphthylmethylene)indene by substitution of the 3-position of the indene ring, whether or not further substituted in the indene ring to any extent, whether or not substituted on the naphthyl ring to any extent.
“(v) 3-phenylacetylindole or 3-benzoylindole by substitution at the nitrogen atom of the indole ring, whether or not further substituted in the indole ring to any extent, whether or not substituted on the phenyl ring to any extent.
“(B) Such term includes–
“(i) 5-(1,1-dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (CP 47,497);
“(ii) 5-(1,1-dimethyloctyl)-2-[(1R,3S)-3-hydroxycyclohexyl]-phenol (cannabicyclohexanol or CP 47,497 C8-homolog);
“(iii) 1-pentyl-3-(1-naphthoyl)indole (JWH 018 and AM678);
“(iv) 1-butyl-3-(1-naphthoyl)indole (JWH 073);
“(v) 1-hexyl-3-(1-naphthoyl)indole (JWH 019);
“(vi) 1-[2-(4-morpholinyl)ethyl]-3-(1-naphthoyl)indole (JWH 200);
“(vii) 1-pentyl-3-(2-methoxyphenylacetyl)indole (JWH 250);
“(viii) 1-pentyl-3-[1-(4-methoxynaphthoyl)]indole (JWH 081);
“(ix) 1-pentyl-3-(4-methyl-1-naphthoyl)indole (JWH 122);
“(x) 1-pentyl-3-(4-chloro-1-naphthoyl)indole (JWH 398);
“(xi) 1-(5-fluoropentyl)-3-(1-naphthoyl)indole (AM2201);
“(xii) 1-(5-fluoropentyl)-3-(2-iodobenzoyl)indole (AM694);
“(xiii) 1-pentyl-3-[(4-methoxy)-benzoyl]indole (SR 19 and RCS 4);
“(xiv) 1-cyclohexylethyl-3-(2-methoxyphenylacetyl)indole (SR 18 and RCS 8); and
“(xv) 1-pentyl-3-(2-chlorophenylacetyl)indole (JWH 203).”.
(b) Other Drugs.–Schedule I of section 202(c) of the Controlled Substances Act (21 U.S.C. 812(c)) is amended in subsection (c) by adding at the end the following:
“(18) 4-methylmethcathinone (Mephedrone).
“(19) 3,4-methylenedioxypyrovalerone (MDPV).
“(20) 2-(2,5-Dimethoxy-4-ethylphenyl)ethanamine (2C E).
“(21) 2-(2,5-Dimethoxy-4-methylphenyl)ethanamine (2C D).
“(22) 2-(4-Chloro-2,5-dimethoxyphenyl)ethanamine (2C C).
“(23) 2-(4-Iodo-2,5-dimethoxyphenyl)ethanamine (2C I).
“(24) 2-[4-(Ethylthio)-2,5-dimethoxyphenyl]ethanamine (2C T 2).
“(25) 2-[4-(Isopropylthio)-2,5-dimethoxyphenyl]ethanamine (2C T 4).
“(26) 2-(2,5-Dimethoxyphenyl)ethanamine (2C H).
“(27) 2-(2,5-Dimethoxy-4-nitro-phenyl)ethanamine (2C N).
“(28) 2-(2,5-Dimethoxy-4-(n)-propylphenyl)ethanamine (2C P).”.